Pesquisa | Secretaria de Estado da Saúde

1.

Pathogen protein modularity enables elaborate mimicry of a host phosphatase.

Li, Hui; Wang, Jinlong; Kuan, Tung Ariel; Tang, Bozeng; Feng, Li; Wang, Jiuyu; Cheng, Zhi; Sklenar, Jan; Derbyshire, Paul; Hulin, Michelle; Li, Yufei; Zhai, Yi; Hou, Yingnan; Menke, Frank L H; Wang, Yanli; Ma, Wenbo.

Cell ; 186(15): 3196-3207.e17, 2023 07 20.

Artigo Inglês | MEDLINE | ID: mdl-37369204

2.

Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.

Williams, Wilton B; Meyerhoff, R Ryan; Edwards, R J; Li, Hui; Manne, Kartik; Nicely, Nathan I; Henderson, Rory; Zhou, Ye; Janowska, Katarzyna; Mansouri, Katayoun; Gobeil, Sophie; Evangelous, Tyler; Hora, Bhavna; Berry, Madison; Abuahmad, A Yousef; Sprenz, Jordan; Deyton, Margaret; Stalls, Victoria; Kopp, Megan; Hsu, Allen L; Borgnia, Mario J; Stewart-Jones, Guillaume B E; Lee, Matthew S; Bronkema, Naomi; Moody, M Anthony; Wiehe, Kevin; Bradley, Todd; Alam, S Munir; Parks, Robert J; Foulger, Andrew; Oguin, Thomas; Sempowski, Gregory D; Bonsignori, Mattia; LaBranche, Celia C; Montefiori, David C; Seaman, Michael; Santra, Sampa; Perfect, John; Francica, Joseph R; Lynn, Geoffrey M; Aussedat, Baptiste; Walkowicz, William E; Laga, Richard; Kelsoe, Garnett; Saunders, Kevin O; Fera, Daniela; Kwong, Peter D; Seder, Robert A; Bartesaghi, Alberto; Shaw, George M.

Cell ; 184(11): 2955-2972.e25, 2021 05 27.

Artigo Inglês | MEDLINE | ID: mdl-34019795

3.

Dectin-1 signaling on colonic Î³Î´ T cells promotes psychosocial stress responses.

Zhu, Xiaolei; Sakamoto, Shinji; Ishii, Chiharu; Smith, Matthew D; Ito, Koki; Obayashi, Mizuho; Unger, Lisa; Hasegawa, Yuto; Kurokawa, Shunya; Kishimoto, Taishiro; Li, Hui; Hatano, Shinya; Wang, Tza-Huei; Yoshikai, Yasunobu; Kano, Shin-Ichi; Fukuda, Shinji; Sanada, Kenji; Calabresi, Peter A; Kamiya, Atsushi.

Nat Immunol ; 24(4): 625-636, 2023 04.

Artigo Inglês | MEDLINE | ID: mdl-36941398

4.

Fate mapping of Spp1 expression reveals age-dependent plasticity of disease-associated microglia-like cells after brain injury.

Lan, Yangning; Zhang, Xiaoxuan; Liu, Shaorui; Guo, Chen; Jin, Yuxiao; Li, Hui; Wang, Linyixiao; Zhao, Jinghong; Hao, Yilin; Li, Zhicheng; Liu, Zhaoyuan; Ginhoux, Florent; Xie, Qi; Xu, Heping; Jia, Jie-Min; He, Danyang.

Immunity ; 57(2): 349-363.e9, 2024 Feb 13.

Artigo Inglês | MEDLINE | ID: mdl-38309272

5.

Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19.

Hua, Junjie Tony; Ahmed, Musaddeque; Guo, Haiyang; Zhang, Yuzhe; Chen, Sujun; Soares, Fraser; Lu, Jennifer; Zhou, Stanley; Wang, Miranda; Li, Hui; Larson, Nicholas B; McDonnell, Shannon K; Patel, Parasvi S; Liang, Yi; Yao, Cindy Q; van der Kwast, Theodorus; Lupien, Mathieu; Feng, Felix Y; Zoubeidi, Amina; Tsao, Ming-Sound; Thibodeau, Stephen N; Boutros, Paul C; He, Housheng Hansen.

Cell ; 174(3): 564-575.e18, 2018 07 26.

Artigo Inglês | MEDLINE | ID: mdl-30033362

6.

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Quigley, David A; Dang, Ha X; Zhao, Shuang G; Lloyd, Paul; Aggarwal, Rahul; Alumkal, Joshi J; Foye, Adam; Kothari, Vishal; Perry, Marc D; Bailey, Adina M; Playdle, Denise; Barnard, Travis J; Zhang, Li; Zhang, Jin; Youngren, Jack F; Cieslik, Marcin P; Parolia, Abhijit; Beer, Tomasz M; Thomas, George; Chi, Kim N; Gleave, Martin; Lack, Nathan A; Zoubeidi, Amina; Reiter, Robert E; Rettig, Matthew B; Witte, Owen; Ryan, Charles J; Fong, Lawrence; Kim, Won; Friedlander, Terence; Chou, Jonathan; Li, Haolong; Das, Rajdeep; Li, Hui; Moussavi-Baygi, Ruhollah; Goodarzi, Hani; Gilbert, Luke A; Lara, Primo N; Evans, Christopher P; Goldstein, Theodore C; Stuart, Joshua M; Tomlins, Scott A; Spratt, Daniel E; Cheetham, R Keira; Cheng, Donavan T; Farh, Kyle; Gehring, Julian S; Hakenberg, Jörg; Liao, Arnold; Febbo, Philip G.

Cell ; 174(3): 758-769.e9, 2018 07 26.

Artigo Inglês | MEDLINE | ID: mdl-30033370

7.

Retinoid X receptor gamma dictates the activation threshold of group 2 innate lymphoid cells and limits type 2 inflammation in the small intestine.

Zang, Yang; Liu, Shaorui; Rao, Zebing; Wang, Yinsheng; Zhang, Boya; Li, Hui; Cao, Yingjiao; Zhou, Jie; Shen, Zhuxia; Duan, Shengzhong; He, Danyang; Xu, Heping.

Immunity ; 56(11): 2542-2554.e7, 2023 Nov 14.

Artigo Inglês | MEDLINE | ID: mdl-37714152

8.

A GAPDH serotonylation system couples CD8⁺ T cell glycolytic metabolism to antitumor immunity.

Wang, Xu; Fu, Sheng-Qiao; Yuan, Xiao; Yu, Feng; Ji, Qian; Tang, Hao-Wen; Li, Rong-Kun; Huang, Shan; Huang, Pei-Qi; Qin, Wei-Ting; Zuo, Hao; Du, Chang; Yao, Lin-Li; Li, Hui; Li, Jun; Li, Dong-Xue; Yang, Yan; Xiao, Shu-Yu; Tulamaiti, Aziguli; Wang, Xue-Feng; Dai, Chun-Hua; Zhang, Xu; Jiang, Shu-Heng; Hu, Li-Peng; Zhang, Xue-Li; Zhang, Zhi-Gang.

Mol Cell ; 84(4): 760-775.e7, 2024 Feb 15.

Artigo Inglês | MEDLINE | ID: mdl-38215751

9.

The E3 ligases Itch and WWP2 cooperate to limit T_H2 differentiation by enhancing signaling through the TCR.

Aki, Daisuke; Li, Hui; Zhang, Wen; Zheng, Mingke; Elly, Chris; Lee, Jee H; Zou, Weiguo; Liu, Yun-Cai.

Nat Immunol ; 19(7): 766-775, 2018 07.

Artigo Inglês | MEDLINE | ID: mdl-29925997

10.

Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability.

Burnett, Deborah L; Jackson, Katherine J L; Langley, David B; Aggrawal, Anupria; Stella, Alberto Ospina; Johansen, Matt D; Balachandran, Harikrishnan; Lenthall, Helen; Rouet, Romain; Walker, Gregory; Saunders, Bernadette M; Singh, Mandeep; Li, Hui; Henry, Jake Y; Jackson, Jennifer; Stewart, Alastair G; Witthauer, Franka; Spence, Matthew A; Hansbro, Nicole G; Jackson, Colin; Schofield, Peter; Milthorpe, Claire; Martinello, Marianne; Schulz, Sebastian R; Roth, Edith; Kelleher, Anthony; Emery, Sean; Britton, Warwick J; Rawlinson, William D; Karl, Rudolfo; Schäfer, Simon; Winkler, Thomas H; Brink, Robert; Bull, Rowena A; Hansbro, Philip M; Jäck, Hans-Martin; Turville, Stuart; Christ, Daniel; Goodnow, Christopher C.

Immunity ; 54(12): 2908-2921.e6, 2021 12 14.

Artigo Inglês | MEDLINE | ID: mdl-34788600

11.

Improving prime editing with an endogenous small RNA-binding protein.

Yan, Jun; Oyler-Castrillo, Paul; Ravisankar, Purnima; Ward, Carl C; Levesque, Sébastien; Jing, Yangwode; Simpson, Danny; Zhao, Anqi; Li, Hui; Yan, Weihao; Goudy, Laine; Schmidt, Ralf; Solley, Sabrina C; Gilbert, Luke A; Chan, Michelle M; Bauer, Daniel E; Marson, Alexander; Parsons, Lance R; Adamson, Britt.

Nature ; 628(8008): 639-647, 2024 Apr.

Artigo Inglês | MEDLINE | ID: mdl-38570691

12.

A single photoreceptor splits perception and entrainment by cotransmission.

Xiao, Na; Xu, Shuang; Li, Ze-Kai; Tang, Min; Mao, Renbo; Yang, Tian; Ma, Si-Xing; Wang, Peng-Hao; Li, Meng-Tong; Sunilkumar, Ajay; Rouyer, François; Cao, Li-Hui; Luo, Dong-Gen.

Nature ; 623(7987): 562-570, 2023 Nov.

Artigo Inglês | MEDLINE | ID: mdl-37880372

13.

Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers.

Pauthner, Matthias G; Nkolola, Joseph P; Havenar-Daughton, Colin; Murrell, Ben; Reiss, Samantha M; Bastidas, Raiza; Prévost, Jérémie; Nedellec, Rebecca; von Bredow, Benjamin; Abbink, Peter; Cottrell, Christopher A; Kulp, Daniel W; Tokatlian, Talar; Nogal, Bartek; Bianchi, Matteo; Li, Hui; Lee, Jeong Hyun; Butera, Salvatore T; Evans, David T; Hangartner, Lars; Finzi, Andrés; Wilson, Ian A; Wyatt, Richard T; Irvine, Darrell J; Schief, William R; Ward, Andrew B; Sanders, Rogier W; Crotty, Shane; Shaw, George M; Barouch, Dan H; Burton, Dennis R.

Immunity ; 50(1): 241-252.e6, 2019 01 15.

Artigo Inglês | MEDLINE | ID: mdl-30552025

14.

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Quigley, David A; Dang, Ha X; Zhao, Shuang G; Lloyd, Paul; Aggarwal, Rahul; Alumkal, Joshi J; Foye, Adam; Kothari, Vishal; Perry, Marc D; Bailey, Adina M; Playdle, Denise; Barnard, Travis J; Zhang, Li; Zhang, Jin; Youngren, Jack F; Cieslik, Marcin P; Parolia, Abhijit; Beer, Tomasz M; Thomas, George; Chi, Kim N; Gleave, Martin; Lack, Nathan A; Zoubeidi, Amina; Reiter, Robert E; Rettig, Matthew B; Witte, Owen; Ryan, Charles J; Fong, Lawrence; Kim, Won; Friedlander, Terence; Chou, Jonathan; Li, Haolong; Das, Rajdeep; Li, Hui; Moussavi-Baygi, Ruhollah; Goodarzi, Hani; Gilbert, Luke A; Lara, Primo N; Evans, Christopher P; Goldstein, Theodore C; Stuart, Joshua M; Tomlins, Scott A; Spratt, Daniel E; Cheetham, R Keira; Cheng, Donavan T; Farh, Kyle; Gehring, Julian S; Hakenberg, Jörg; Liao, Arnold; Febbo, Philip G.

Cell ; 175(3): 889, 2018 10 18.

Artigo Inglês | MEDLINE | ID: mdl-30340047

15.

Hypocrystalline ceramic aerogels for thermal insulation at extreme conditions.

Guo, Jingran; Fu, Shubin; Deng, Yuanpeng; Xu, Xiang; Laima, Shujin; Liu, Dizhou; Zhang, Pengyu; Zhou, Jian; Zhao, Han; Yu, Hongxuan; Dang, Shixuan; Zhang, Jianing; Zhao, Yingde; Li, Hui; Duan, Xiangfeng.

Nature ; 606(7916): 909-916, 2022 06.

Artigo Inglês | MEDLINE | ID: mdl-35768591

16.

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.

Lim, Hwee Ying; Lim, Sheau Yng; Tan, Chek Kun; Thiam, Chung Hwee; Goh, Chi Ching; Carbajo, Daniel; Chew, Samantha Hui Shang; See, Peter; Chakarov, Svetoslav; Wang, Xiao Nong; Lim, Li Hui; Johnson, Louise A; Lum, Josephine; Fong, Chui Yee; Bongso, Ariff; Biswas, Arijit; Goh, Chern; Evrard, Maximilien; Yeo, Kim Pin; Basu, Ranu; Wang, Jun Kit; Tan, Yingrou; Jain, Rohit; Tikoo, Shweta; Choong, Cleo; Weninger, Wolfgang; Poidinger, Michael; Stanley, Richard E; Collin, Matthew; Tan, Nguan Soon; Ng, Lai Guan; Jackson, David G; Ginhoux, Florent; Angeli, Véronique.

Immunity ; 49(2): 326-341.e7, 2018 08 21.

Artigo Inglês | MEDLINE | ID: mdl-30054204

17.

Non-KREEP origin for Chang'e-5 basalts in the Procellarum KREEP Terrane.

Tian, Heng-Ci; Wang, Hao; Chen, Yi; Yang, Wei; Zhou, Qin; Zhang, Chi; Lin, Hong-Lei; Huang, Chao; Wu, Shi-Tou; Jia, Li-Hui; Xu, Lei; Zhang, Di; Li, Xiao-Guang; Chang, Rui; Yang, Yue-Heng; Xie, Lie-Wen; Zhang, Dan-Ping; Zhang, Guang-Liang; Yang, Sai-Hong; Wu, Fu-Yuan.

Nature ; 600(7887): 59-63, 2021 12.

Artigo Inglês | MEDLINE | ID: mdl-34666339

18.

Phosphorylated RB Promotes Cancer Immunity by Inhibiting NF-κB Activation and PD-L1 Expression.

Jin, Xin; Ding, Donglin; Yan, Yuqian; Li, Hui; Wang, Bo; Ma, Linlin; Ye, Zhenqing; Ma, Tao; Wu, Qiang; Rodrigues, Daniel N; Kohli, Manish; Jimenez, Rafael; Wang, Liguo; Goodrich, David W; de Bono, Johann; Dong, Haidong; Wu, Heshui; Zhu, Runzhi; Huang, Haojie.

Mol Cell ; 73(1): 22-35.e6, 2019 01 03.

Artigo Inglês | MEDLINE | ID: mdl-30527665

19.

Postsynaptic receptors regulate presynaptic transmitter stability through transsynaptic bridges.

Godavarthi, Swetha K; Hiramoto, Masaki; Ignatyev, Yuri; Levin, Jacqueline B; Li, Hui-Quan; Pratelli, Marta; Borchardt, Jennifer; Czajkowski, Cynthia; Borodinsky, Laura N; Sweeney, Lora; Cline, Hollis T; Spitzer, Nicholas C.

Proc Natl Acad Sci U S A ; 121(15): e2318041121, 2024 Apr 09.

Artigo Inglês | MEDLINE | ID: mdl-38568976

20.

SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling.

Otter, Clayton J; Bracci, Nicole; Parenti, Nicholas A; Ye, Chengjin; Asthana, Abhishek; Blomqvist, Ebba K; Tan, Li Hui; Pfannenstiel, Jessica J; Jackson, Nathaniel; Fehr, Anthony R; Silverman, Robert H; Burke, James M; Cohen, Noam A; Martinez-Sobrido, Luis; Weiss, Susan R.

Proc Natl Acad Sci U S A ; 121(15): e2320194121, 2024 Apr 09.

Artigo Inglês | MEDLINE | ID: mdl-38568967

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Pathogen protein modularity enables elaborate mimicry of a host phosphatase.

Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.

Dectin-1 signaling on colonic Î³Î´ T cells promotes psychosocial stress responses.

Fate mapping of Spp1 expression reveals age-dependent plasticity of disease-associated microglia-like cells after brain injury.

Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19.

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Retinoid X receptor gamma dictates the activation threshold of group 2 innate lymphoid cells and limits type 2 inflammation in the small intestine.

A GAPDH serotonylation system couples CD8⁺ T cell glycolytic metabolism to antitumor immunity.

The E3 ligases Itch and WWP2 cooperate to limit T_H2 differentiation by enhancing signaling through the TCR.

Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability.

Improving prime editing with an endogenous small RNA-binding protein.

A single photoreceptor splits perception and entrainment by cotransmission.

Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers.

Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

Hypocrystalline ceramic aerogels for thermal insulation at extreme conditions.

Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen.

Non-KREEP origin for Chang'e-5 basalts in the Procellarum KREEP Terrane.

Phosphorylated RB Promotes Cancer Immunity by Inhibiting NF-κB Activation and PD-L1 Expression.

Postsynaptic receptors regulate presynaptic transmitter stability through transsynaptic bridges.

SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling.